Dr. Zsengeller is an expert on experimental histologic and immunohistochemical correlates of pathophysiology in various rodent and large animal experimental disease models. She also serves as an Instructor at Harvard Medical School in the Division of Molecular Medicine, Beth Israel Deaconess Medical Center (Boston, MA) where she studies inflammation, oxidative stress, and signaling pathways involved in kidney disease.
Dr. Zsengeller has an extensive background in immunohistochemistry and related techniques, gained during her Research Fellowships at Cincinnati Children’s Hospital, and has applied these to her study of signalling mechanisms in lung inflammation, both in Cincinnati and at Harvard Medical School. This work involved, interalia, mechanisms of adenovirus-and hyperoxia- induced inflammation, and the study of Toll-Like receptors. In addition, Dr. Zsengeller established and ran the histology section at Inotek Pharmaceuticals Corporation, working on mediators of oxidative and nitrosative stress, including PARP, in cardiovascular disease, diabetes, and numerous other therapeutic areas. Dr. Zsengeller joined Radikal Therapeutics in 2012 and currently leads its histology and immunohistochemistry programs.